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Mixed Agonist/Antagonist and Partial Agonist Opioid Analgesics The concomitant utilization of opioids with other opioid analgesics, like butorphanol, nalbuphine, pentazocine, may well lessen the analgesic impact of oxycodone and acetaminophen tablets and/or precipitate withdrawal symptoms. Suggest patient to prevent concomitant use of those drugs.i